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CELIAC

WHAT IS CELIAC?


Celiac disease is an inherited, autoimmune disease in which the lining of the small intestine is damaged form proteins found in wheat, barley , rye, and oats. These proteins are part of the make-up of gluten which is what gives dough the elasticity and part of the ability to rise. The symptoms of this disease may not show up until there is a large stressor in one's life, such as pregnancy, a major illness, death of a family member, divorce or any other big life stress. Recent studies have confirmed that there is another form of this disease that is call the "Silent Celiac disease". There are not the usual gut symptoms of traditional Celiac disease, but more neurological symptoms. This type of Celiac disease(CD) is much more difficult to diagnose.

43% OF Americans are genetically predisposed to celiac disease and 81 % are predisposed to gluten intolerance.


CD affects up to one in 100 Americans, although only one in 8 are estimated to be aware or their condition, as symptoms are often silent, as in the "Silent Celiac Disease".

Signs of Celiac Disease are usually described with digestive distres and abdominal pain. However, research has found that one can have celiac with none of these symptoms whatsoever. This is called atypical or SILENT CELIAC and the symptoms can be different with different age groups

SYMPTOMS OF CELIAC

Infancy (less than 2 years of age)

  • Diarrhea
  • Abdominal bloating
  • Failure to thrive
  • Anorexia
  • Muscle wasting


Childhood

  • Anemia
  • Diarrhea or constipation
  • Loss of appetite (short statue, osteoporosis)


Adulthood

  • Diarrhea or constipation
  • Anemia
  • Tongue and mouth sores
  • Fatigue, infertility
  • Neuro-psychiatric symptoms (anxiety, depression)
  • Bone pain (osteoperosis)
  • Weakness (myopathy, neuropathy)
  • Dermatitis herpetiformis - itchy, blistery rash


Neurological symptoms of CD in adults:

  • Ataxia (balance disturbances, difficulty walking)
  • Neuropathies (peripheral - tingling in arms and legs)
  • Axonal neuropathy
  • Migraines
  • Epileptic seizures
  • Myopathies
  • Neuromyotonia

Other autoimmune diseases associated with CD:

  • Diabetes type 1
  • Hashimoto's thyroiditis
  • Sjogrens Disease
  • Alopecia Areata
  • Liver disease-autoimmune
  • SLE
  • RA
  • Fibromyalgia
  • MS
  • Dental enamel defects
  • Raynaud's syndrone

THE BEST CELIAC TEST

The current common test for celiac is very poor and only tests for one of the peptides (part of a protein) in the gluten. This will only test positive in 50% of celiac patients. There is a new test available only since 2011 that is not only more sensitive and accurate, but tests for 12 different peptides in the gluten molecule, not just gliaden. You can order this test for 24 antibodies to the 12 peptides, listed below, through our office. The blood sample is sent to Cyrex Labs for processing.

Wheat/Gluten Proteome Reactivity & Autoimmunity Test

  • Wheat IgG
  • Wheat IgA
  • Wheat Germ Agglutinin IgG
  • Wheat Germ Agglutinin IgA
  • Alpha Gliadin 17 MER IgG
  • Alpha Gliadin 17 MER IgA
  • Deamidated Alpha Gliadin 33 MER IgG
  • Deamidated Alpha Gliadin 33 MER IgA
  • Prodynorphin IgG
  • Prodynorphin IgA
  • Gliadin-Transglutaminase IgG
  • Gliadin-Transglutaminase IgA
  • Transglutaminase IgG
  • Transglutaminase IgA
  • Glutamic Acid Decarboxylase (GAD65) IgG
  • Glutamic Acid Decarboxylase (GAD65) IgA
  • Gamma Gliadin 15 MER IgG
  • Gamma Gliadin 15 MER
  • Omega Gliadin IgG
  • Omega Gliadin IgA
  • Glutenin IgG
  • Glutenin IgA
  • Gluteomorphin IgG
  • Gluteomorphin IgA



























 

Research

"The current diagnostic criteria of coeliac disease require the presence of small intestinal mucosal villous atrophy and crypt hyperplasia.2 However, villous atrophy comprises only the end stage in the clinical course of the disease: evidence shows that coeliac disease develops gradually from small bowel mucosal inflammation to crypt hyperplasia and finally to overt villous atrophy.6 "

*CD affects up to one in 100 Americans, although only one in 8 are estimated to be aware of their condition, as symptoms are often silent, as in the " Silent Celiac Disease".


 

     
 

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